Speed-Dependent Cellular Decision Making in Nonequilibrium Genetic Circuits
نویسندگان
چکیده
منابع مشابه
Speed-Dependent Cellular Decision Making in Nonequilibrium Genetic Circuits
Despite being governed by the principles of nonequilibrium transitions, gene expression dynamics underlying cell fate decision is poorly understood. In particular, the effect of signaling speed on cellular decision making is still unclear. Here we show that the decision between alternative cell fates, in a structurally symmetric circuit, can be biased depending on the speed at which the system ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0032779